Arcoxia Dosage/Direction for Use

Arcoxia is administered orally. It may be taken with or without food. Recommended Dose: Arthritis/Osteoarthritis: 60 mg once daily. Analgesia/Acute Pain Associated with Dental Surgery: 120 mg once daily. Arcoxia 120 mg should be used only for the acute symptomatic period.
Chronic Musculoskeletal Pain: 60 mg once daily.
Doses greater than those recommended for each indication have either not demonstrated additional efficacy or have not been studied. Therefore, the dose for each indication is the maximum recommended dose.
Hepatic Insufficiency: In patients with mild hepatic insufficiency (Child-Pugh score 5-6), a dose of 60 mg once daily should not be exceeded. In patients with moderate hepatic insufficiency (Child-Pugh score 7-9), the dose should be reduced; a dose of 60 mg every other day should not be exceeded. There are no clinical or pharmacokinetic data in patients with severe hepatic insufficiency (Child-Pugh score >9). (See Precautions.)
Renal Insufficiency: In patients with advanced renal disease (CrCl <30 mL/min), treatment with Arcoxia is not recommended. No dosage adjustment is necessary for patients with lesser degrees of renal insufficiency (CrCl ≥30 mL/min). (See Precautions.)
Elderly, Gender, Race: No dosage adjustment in Arcoxia is necessary.