Pregnancy: Pregnancy category: C.
There are no adequate and well-controlled studies of ticagrelor use in pregnant women. Ticagrelor should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Lactation: It is not known whether ticagrelor or its active metabolites are excreted in human milk. Because many drugs are excreted in human milk, and because of the potential for serious adverse reactions in nursing infants from ticagrelor, a decision should be made whether to discontinue nursing or to discontinue drug.