Not for rapid relief of bronchospasm & not suitable as sole therapy in the treatment of status asthmaticus or other acute exacerbations of asthma where intensive measures are required. Patients being transferred from oral corticosteroids to budesonide; who have required high dose emergency corticosteroid therapy, prolonged treatment at the highest recommended dose of inhaled corticosteroids or receiving medication metabolized by CYP3A4. May regain rhinitis & eczema when transferred from oral therapy. HPA axis suppression (including dose-dependent), bone density reduction, cataracts, glaucoma, retardation of growth rate in childn. Monitor for signs of adrenal dysfunction. Not to be used as long-term treatment in childn. Initial reduction of growth velocity w/in the 1st yr of treatment may occur in childn. Patients should be titrated to the lowest effective dose. May mask some signs of existing infection & new infections may appear. Special care is needed in patients w/ active or quiescent pulmonary TB or fungal, bacterial or viral infections of the resp system. Not to be used w/ positive pressure delivery systems in pulmonary conditions involving pneumothorax, air cysts or mediastinal emphysema unless special drainage is performed. Severely compromised liver function. Pregnancy.