Camelon 8

Camelon 8

methylprednisolone

Manufacturer:

Caprifarmindo

Marketer:

Caprifarmindo
Concise Prescribing Info
Contents
Methylprednisolone
Indications/Uses
Bronchial asthma, allergic rhinitis, urticaria, eczema or dermatitis, acute rheumatic fever, RA, acquired (autoimmune) hemolytic anemia, idiopathic thrombocytopenic purpura in adults, myeloblastosis, lymphogranulomatosis, ulcerative colitis, nephrotic syndrome, skin diseases, lupus erythematosus, dermatomyositis. Suppression of the immune response after transplantations. Adjuvant in treatment w/ cytostatic agents or in radiotherapy. Substitution in primary adrenocortical insufficiency & after adrenalectomy.
Dosage/Direction for Use
Adult Initial dose: 4-80 mg daily. Maintenance dose: 4-8 mg daily, may be increased up to 16 mg daily. Childn Initial dose: 0.8-1.1 mg/kg. Maintenance dose: 2-4 mg daily, may be increased up to 8 mg daily. Adjuvant to mineralocorticoid therapy in Addison's disease Substitution dose: 4-8 mg in stressful situation, up to 16 mg daily.
Administration
Should be taken with food.
Contraindications
Hypersensitivity to methylprednisolone or other glucocorticoids. Gastric ulcers, osteoporosis, psychiatric disorders, amebiasis, systemic mycosis infection, poliomyelitis, narrow or open-angle glaucoma & viral diseases.
Special Precautions
Patients w/ severe HTN & cardiac insufficiency. May produce subcapsular cataracts, glaucoma & enhance the establishment of fungi or virus infections. Carry out ophth control every 3 mth in long-term treatment. Re-examine blood & urine sugar values in diabetic patients. May mask signs of infection. Not to be discontinued abruptly but gradually. Increase dosage in patients w/ stressful situation. Patients should not receive smallpox or other high-dose vaccines. Monitor carefully patients w/ TB-latent or tuberculine reactivity. May potentiate glucocorticoid effects in patients w/ hypothyroid or hepatic cirrhosis. Not recommended for pregnant women & nursing mothers. May inhibit growth & development w/ prolonged use in childn.
Adverse Reactions
Moon face, trunk obesity, muscular weakness, HTN, osteoporosis, reduced glucose tolerance, DM, sex hormone secretion disorder, peptic ulcer, antibody response impairment, growth retardation in childn, glaucoma, cataract, thrombosis, pancreatitis; headache, vertigo, increased intracranial pressure w/ papilledema; electrolyte disturbance, fluid retention; dermatologic & immunologic disturbance.
Drug Interactions
May potentiate/increase glycoside effect w/ cardiac glycosides. May potentiate/increase K-depleting effect w/ diuretics. Reduced hypoglycaemic effect of antidiabetic agents & anticoagulant effect of coumarin derivatives. Reduced corticosteroid effect w/ rifampicin, phenytoin or barbiturates. May potentiate/increase clearance of chronic high-dose acetosal. Convulsions w/ cyclosporin. Decreased clearance w/ ketoconazole & troleandomycin.
ATC Classification
H02AB04 - methylprednisolone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Presentation/Packing
Form
Camelon 8 tab 8 mg
Packing/Price
10 × 10's (Rp291,550/boks)
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