Caprifim

Caprifim

cefepime

Manufacturer:

Caprifarmindo
Concise Prescribing Info
Contents
Cefepime
Indications/Uses
Adult ≥16 yr: Lower resp tract (pneumonia & bronchopneumonia), skin & skin structure, intra-abdominal (peritonitis, biliary tract infection), severe or complicated gynecological infections; septicemia; empiric treatment in febrile neutropenia. Childn 2 mth-<16 yr: Severe pneumonia, empiric treatment in febrile neutropenia, complicated upper (pyelonephritis) & lower UTI.
Dosage/Direction for Use
Adult Mild to moderate UTI 500 mg-1 g IM/IV. Mild to moderate infections except UTI 1 g IM/IV. Severe infections including skin & skin structure infections 2 g IV. Doses are given 12 hrly. Very severe or life-threatening infections 2 g IV 8 hrly. IV doses should be given approx over 30 min. Childn 2 mth-<16 yr w/ ≤40 kg body wt Pneumonia, UTI, skin & skin structure infections; empiric therapy for febrile neutropenia 50 mg/kg/dose 12 hrly for 7-10 days. Febrile neutropenic patient 50 mg/kg/dose 8 hrly for 7-10 days.
Contraindications
Hypersensitivity to cephalosporins, penicillins or other β-lactams.
Special Precautions
Impaired renal function (CrCl ≤50 mL/min); superinfection. Discontinue in case of allergic reactions or mild case of pseudomembranous colitis. Pregnancy & lactation. Elderly.
Adverse Reactions
Rash, pruritus, urticaria, nausea, vomiting, oral moniliasis, diarrhea, colitis, headache, fever, vaginitis, erythema; abdominal pain, constipation, vasodilation, dyspnea, dizziness, paresthesia, genital pruritus, taste perversion, chills & unspecified moniliasis; phlebitis & inflammation at inj site; transient BUN &/or serum creatinine elevations, thrombocytopenia, leucopenia, neutropenia; Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, toxic nephropathy, aplastic anemia, hemolytic anemia, hemorrhage.
Drug Interactions
Aminoglycosides & potent diuretics may cause nephrotoxicity. Ampicillin, metronidazole, vancomycin, gentamicin, tobramycin, netilmicin sulfate, aminophylline.
MIMS Class
Cephalosporins
ATC Classification
J01DE01 - cefepime ; Belongs to the class of fourth generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Caprifim inj 1 g
Packing/Price
1's (Rp275,500/boks)
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