Discontinue treatment if GI bleeding or perforation, serious allergic reactions occur. Patient requiring low dose ASA. Concomitant use w/ corticosteroids, anticoagulants, anti-platelet agents or SSRIs. Patients w/ symptoms or history of GI disease, ulcerative colitis or Crohn's disease, asthma, seasonal allergic rhinitis or chronic pulmonary disease. Post GI surgery. Periodic re-evaluation & dose adjustment in patients w/ established heart disease (NYHA I), HTN, or significant CV risk factors. Monitor BP during initiation & through out the treatment course. Monitor blood counts, liver function during prolonged treatment. Avoid use w/ other systemic NSAIDs including COX-2 inhibitors. May mask signs & symptoms of infection. Monitor patients w/ haemostasis defects. Severe fluid retention & edema. Monitor renal function in patients w/ history of HTN, impaired cardiac or renal function, extracellular vol depletion, elderly, receiving diuretics or other drugs that impact renal function. Patients w/ hepatic porphyria. Cataflam Fast
Not recommended in childn & adolescent <14 yr.