Chenodeoxycholic acid - oral

Patient Medicine Information
Why do I need this medicine?
Chenodeoxycholic acid is used on its own or together with other medicines to treat cholesterol gallstones (abnormal stone-like mass formation in the gall bladder which is composed of undissolved cholesterol).

This medicine may be used to treat other conditions as decided by your doctor.
How do I take this medicine?
Take this medicine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it together with food or immediately after a meal.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your condition.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • liver disease
  • other gall bladder problems
as Chenodeoxycholic acid may not be suitable for you.

Do not take Chenodeoxycholic acid if you are pregnant or planning to have a baby soon. If you become pregnant while being treated with this medicine, alert your doctor immediately. This medicine may cause harm to your unborn child. You must use proven birth control methods while taking Chenodeoxycholic acid.
What should I take note of while taking this medicine?
Let your doctor know if you are breastfeeding.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
  • Routine tests (e.g. liver function, cholesterol levels) may be done while you are being treated with this medicine.
  • X-ray or ultrasound of the gall bladder may be done to monitor the gallstones.
Your doctor will advise you about how often you need to have these tests.

What lifestyle changes should I make to reduce my cholesterol levels?

A healthy, balanced diet and regular exercise are keys to help you reduce your cholesterol levels. Try to control the type and amount of food that you eat each meal. Include lots of fruits and vegetables in your diet and avoid eating fried foods or foods that are high in fat. If you have not been exercising, start slow and gradually step up your exercise capacity.
What side effects could I experience?
Chenodeoxycholic acid may cause any of the following side effects: diarrhoea, abdominal pain, loss of appetite, constipation, dyspepsia, nausea and vomiting.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following as this may be sign of liver toxicity:
  • yellowing of the skin or eyes with abdominal pain, dark coloured urine, tiredness, swelling in the legs and ankles
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • cholesterol-lowering medicine e.g. cholestyramine, colestipol, clofibrate, fenofibrate
  • medicine to neutralize stomach acid e.g. aluminium hydroxide
  • blood thinning medicine e.g. warfarin
  • birth control pills
The list does not include all medicines that may interact with Chenodeoxcholic acid.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on chenodeoxycholic acid - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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