Clidacor Gel

Clidacor Gel

clindamycin

Manufacturer:

Derma XP
Full Prescribing Info
Contents
Clindamycin.
Description
Each gram of gel contains Clindamycin phosphate equivalent to Clindamycin 10 mg.
Action
Pharmacology: Although Clindamycin phosphate is inactive in vitro, rapid in vivo hydrolysis converts this compound to the antibacterially active Clindamycin. Clindamycin in vitro active to Propionibacterium acnes. Free fatty acids on the skin surface has been decreased from approximately 14% to 2% following application of Clindamycin.
Indications/Uses
For treatment of acne vulgaris.
Dosage/Direction for Use
Apply lightly to the affected skin area twice daily.
Overdosage
No special medications. If allergic reactions occur, the usual agents (corticosteroids, adrenalin, and antihistamine) should be available for emergency treatment.
Contraindications
Patients who have hypersensitivity to Clindamycin.
Patients who have a history of regional enteritis or ulcerative colitis.
Patients who have a history of antibiotic - associated colitis.
Special Precautions
Use of the topical formulation of Clindamycin results in absorption of the antibiotic from the skin surface, so that like administered orally when significant diarrhea occurs, the drug should be discontinued.
Used with caution in patients with atopic individuals.
Used with caution in pregnant and nursing women, this drug should be used only if clearly needed.
Safety and efficacy in pediatric patients under the age of 12 has not been established.
Adverse Reactions
Burning, itching, skin dryness, erythema, oily skin, peeling, skin irritation, gram - negative folliculitis abdominal pain, and gastrointestinal disturbances.
Drug Interactions
Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents, therefore it should be used with caution in patients receiving such agents. In vitro antagonism has been demonstrated between Clindamycin and Erythromycin. It is advised to separate the time of administration of each drug, because it is possible to be clinically significant effect.
Storage
Store below 30°C.
ATC Classification
D10AF01 - clindamycin ; Belongs to the class of topical antiinfective preparations used in the treatment of acne.
Presentation/Packing
Topical gel (tube) 1% x 10 g x 1's.
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