Corifollitropin alfa is used together with other medicines to help achieve pregnancy in women receiving infertility treatment.
Use Corifollitropin alfa exactly as directed by your doctor. Do not use more or less than instructed by your doctor.
Corifollitropin alfa is to be injected subcutaneously (into the fatty layer under the skin, preferably in the abdominal wall). Remember to rotate the injection sites. Do not inject into the same area all the time. New injection sites should be at least 1.5 inches away from the previous injection site.
If you or your caregiver had been given the proper training on the preparation and injection techniques of Corifollitropin alfa, you or your caregiver may do the administration.
Make sure you know how to use this medicine. If you have problems or do not understand the instructions, ask your doctor or pharmacist.
The dose of Corifollitropin alfa will be decided by your doctor. Your doctor will advise you on the course of your treatment depending on your response to the medication.
Ensure that you keep all appointments with your doctor so that you do not miss any dose. Your doctor also needs to regularly monitor your response to Corifollitropin alfa.
If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
If you or a caregiver had been trained to administer this medicine, inject the missed dose as soon as you remember and return to your normal dosing schedule.
DO NOT double a dose under any circumstances.
If you often forget to administer this medicine, let your doctor and pharmacist know.
Alert your doctor if you have the following conditions:
- tumours of the ovary, breast, uterus, pituitary or hypothalamus
- undiagnosed abnormal vaginal bleeding
- ovaries that does not work (primary ovarian failure)
- cysts (sacs of fluid) in the ovaries or enlarged ovaries
- history of ovarian hyperstimulation syndrome (a serious condition that occurs when the ovaries are overly stimulated)
- malformations of the sexual organs
- polycystic ovarian syndrome (PCOS)
as Corifollitropin alfa may not be suitable for you.
Do not use Corifollitropin alfa if you are pregnant or breastfeeding.
Inform your doctor if you have the following conditions:
- kidney disease
- acute porphyria (an inherited disorder that may cause skin or nerve prolems)
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
- To check the appropriateness of Corifollitropin alfa medication, thorough evaluation and assessment before the initiation of the treatment may be needed.
- You may need to have routine tests (e.g. ultrasound, blood tests to measure oestradiol level). Your doctor will advise you about how often you will need to have these tests.
- Regular monitoring of your condition may be needed while you are being treated with Corifollitropin alfa as this medicine may increase your risk of an ectopic pregnancy (a pregnancy in which the foetus develops outside of the womb), multiple births or pregnancy loss.
Corifollitropin alfa may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.
Other side effects include any of the following: pelvic discomfort or pain, headache, nausea, tiredness, breast tenderness.
Some side effects may need immediate medical help. Alert your doctor immediately if you experience:
- abdominal pain, nausea or diarrhoea as these are possible symptoms of ovarian hyperstimulation syndrome (OHSS)
- blood clots
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Store in the refrigerator, between 2-8 °C, away from the reach of children. Do not allow to freeze. If frozen, this medicine may become ineffective and should not be used.
Protect from light. Light may cause the medicine to lose some of its effectiveness.
Medicines must not be used past the expiry date.
Do not use this medicine if it becomes cloudy or if it has changed in colour.
Return any unused or expired medicine to your pharmacist, clinic or hospital for disposal.