Desmopressin - sublingual

Patient Medicine Information
Why do I need this medicine?
Desmopressin is a hormone. It helps control the symptoms of diabetes insipidus (water diabetes) where the body produces an abnormally large amount of urine.

This medicine is also used to control excessive thirst and to reduce the production of an abnormally large amount of urine that occurs after a head injury or after certain types of surgery.

Desmopressin can also be used to treat frequent urination at night.
How do I take this medicine?
Take Desmopressin exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take Desmopressin with or without food. Try to take it at the same time each day.

Do not swallow, chew or crush the tablet; it must be placed under your tongue to be effective. Desmopressin is absorbed into your body through the lining of your mouth.

Desmopressin must be taken regularly for it to be effective. Continue taking it even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have a heart disease as Desmopressin may not be suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:

- hyponatraemia (a low sodium level in the blood)
- high blood pressure
- kidney disease

Let your doctor know if you are pregnant or breastfeeding.

While you are being treated with Desmopressin, you may need to limit the amount of water or other fluids that you take. Your doctor will advise you about how much water or fluid you can take.
What side effects could I experience?
Desmopressin may cause any of the following side effects: headache, stomach pain, nausea and rashes.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:

- medicines to treat depression e.g. fluoxetine, escitalopram, amitriptyline, clomipramine
- NSAIDs (medicines for pain and inflammation) e.g. ibuprofen, indomethacin
- medicines for mood disorders e.g. chlorpromazine, haloperidol, thioridazine
- medicines for epilepsy (seizures or fits) e.g. carbamazepine

This list does not include all medicines that may interact with Desmopressin.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on desmopressin - sublingual and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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