Diaformin XR Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Metformin HCl

Indications/Uses

Monotherapy or adjuvant therapy to diet & exercise to improve glycemic control in patients w/ type 2 DM. Can be given in combination therapy w/ sulfonylurea or insulin to improve blood sugar.

Dosage/Direction for Use

Individualized dosage. Initially 500 mg once daily in the evening. May be gradually increased until max: 2,000 mg daily.

Administration

Should be taken with food: Take w/ meals.

Contraindications

Hypersensitivity. CHF, acute or chronic metabolic acidosis including diabetic ketoacidosis w/ or w/o coma. Patients w/ kidney impairment (serum creatinine 1.5 mg/dL in male & 1.4 mg/dL in female).

Special Precautions

Acute or chronic alcoholism, patients who are undergoing radiologic exam w/ any IV contrast. Patients w/ liver disease. Pregnancy & lactation. Childn. Elderly.

Adverse Reactions

Nausea, vomiting, diarrhea, abdominal pain, constipation, abdominal distention, dyspepsia/heartburn, flatulence; dizziness, headache; upper resp tract infection; taste disturbances.

View ADR Monitoring Form

Drug Interactions

Glyburide, furosemide, nifedipine, cationic agents (eg, amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, vancomycin), other drugs w/ any tendency to cause hyperglycaemia including thiazide & other diuretics, corticosteroid, phenothiazine, thyroid products, estrogen, OC, phenytoin, nicotinic acid, sympathomimetic agents, Ca channel blocker, INH.

MIMS Class

Antidiabetic Agents

ATC Classification

A10BA02 - metformin ; Belongs to the class of biguanides. Used in the treatment of diabetes.

Regulatory Classification

Presentation/Packing

Form

Diaformin XR SR caplet 500 mg

Packing/Price

10 × 10's (Rp200,000/boks)

Diaformin XR

metformin

Manufacturer:

Otto