Diamicron MR 60

Diamicron MR 60

gliclazide

Manufacturer:

Servier
Concise Prescribing Info
Contents
Gliclazide
Indications/Uses
Type 2 diabetes in adult when dietary measures, physical exercise & wt loss alone are insufficient to control blood glucose.
Dosage/Direction for Use
Initially 30 mg once daily (½ tab of Diamicron MR 60). If blood glucose is inadequately controlled, may be increased to 60, 90 or 120 mg daily in successive steps w/ at least 1-mth interval between each increment. Max: 120 mg daily.
Administration
Should be taken with food: Take w/ breakfast. Swallow whole, do not chew/crush.
Contraindications
Hypersensitivity to sulfonamides. Type 1 diabetes; diabetic pre-coma & coma, diabetic ketoacidosis; severe renal or hepatic insufficiency. Treatment w/ miconazole. Lactation.
Special Precautions
Increased risk of hypoglycaemia in malnutrition, irregular meal times, skipping meals, fasting/dietary changes; imbalance between exercise & carbohydrate intake; thyroid disorders, hypopituitarism & adrenal insufficiency. Fever, trauma, infection or surgery. Monitor blood glucose & glycated Hb levels. G6PD-deficiency. Pregnancy.
Adverse Reactions
Hypoglycaemia, GI disturbances including abdominal pain, nausea, vomiting, dyspepsia, diarrhoea & constipation.
Drug Interactions
Miconazole, phenylbutazone, alcohol, other antidiabetic agents, β-blockers, fluconazole, ACE inhibitors, H2-receptor antagonists, MAOIs, sulfonamides, NSAIDs, danazol, chlorpromazine, glucocorticoids, ritodrine, salbutamol, terbutaline, anticoagulants.
MIMS Class
ATC Classification
A10BB09 - gliclazide ; Belongs to the class of sulfonylureas. Used in the treatment of diabetes.
Presentation/Packing
Form
Diamicron MR 60 modified-release tab 60 mg
Packing/Price
30's (Rp170,100/pak)
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