Life-threatening digoxin intoxication
Adult: Each vial containing 38 mg of purified lyophilised digoxin-specific Fab fragments. For acute ingestion of unknown amount: Usually, 20 vials is adequate to treat most life-threatening ingestions, may give as a single dose or give 10 vials, observe response, then give a second 10-vial dose if needed. For acute ingestion of known amount: Based on number of tablets/capsules ingested, the number of vials needed can be calculated by taking the total amount of digoxin ingested (mg) divided by 0.5. Dose to be given via IV inj over 30 min; bolus inj may be used if cardiac arrest is imminent. For more detailed information: Refer to full prescribing information.
Child: Each vial containing 38 mg of purified lyophilised digoxin-specific Fab fragments. For acute ingestion of unknown amount: Usually, 20 vials is adequate to treat most life-threatening ingestions, may give as a single dose or give 10 vials, observe response, then give a second 10-vial dose if needed. For acute ingestion of known amount: Based on number of tablets/capsules ingested, the number of vials needed can be calculated by taking the total amount of digoxin ingested (mg) divided by 0.5. Dose to be given via IV inj over 30 min; bolus inj may be used if cardiac arrest is imminent. For more detailed information: Refer to full prescribing information.
Child: Each vial containing 38 mg of purified lyophilised digoxin-specific Fab fragments. For acute ingestion of unknown amount: Usually, 20 vials is adequate to treat most life-threatening ingestions, may give as a single dose or give 10 vials, observe response, then give a second 10-vial dose if needed. For acute ingestion of known amount: Based on number of tablets/capsules ingested, the number of vials needed can be calculated by taking the total amount of digoxin ingested (mg) divided by 0.5. Dose to be given via IV inj over 30 min; bolus inj may be used if cardiac arrest is imminent. For more detailed information: Refer to full prescribing information.