Metastatic breast cancer
Adult: 60-75 mg/m2 BSA once every 3 wk in combination with cyclophosphamide given as an infusion over 1 hr diluted in 0.9% sodium chloride or 5% glucose.
AIDS-related Kaposi's sarcoma
Adult: As pegylated liposome: 20 mg/m2 BSA infused over 30 min once every 2-3 wk.
Adult: As pegylated liposome: 50 mg/m2 BSA infused over 1 hr once every 4 wk.
Local malignant neoplasms in the bladder
Adult: 50 ml of a 1 mg/ml solution instilled into the bladder for 1 hr once a mth.