Duphalac initiates the return to a normal physiology of the colon. It may take up to 48 hrs before normal defaecation occurs. The total daily dose is taken preferably during breakfast. The dosage for constipation can be varied according to the individual response, but the following dosage scheme serves as a guide (see table).
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Dosage may be reduced if the desired effect is achieved.
Portal Hepatic Encephalopathy:
Initial Dose: 30-50 mL 3 times daily. Maintenance Dose: To be adjusted to the individual response, diarrhoea must be prevented.
10-25 mL. Children 7-14 years:
10 mL; 1-6 years:
5-10 mL. Infants:
5 mL. All doses are to be taken daily.
May be taken with meals to reduce gastrointestinal discomfort. For constipation and the production of soft stools, preferably taken once during breakfast.