Eclid

Eclid

acarbose

Manufacturer:

Dexa Medica
Concise Prescribing Info
Contents
Acarbose
Indications/Uses
Adjunctive therapy for DM in combination w/ diet.
Dosage/Direction for Use
Initially 50 mg 3 times daily. Then increase dose to 200 mg 3 times daily. Max: 200 mg 3 times daily. Increased at intervals of 4-8 wk or more. Adjust dose according to individual response.
Administration
Should be taken with food: Take immediately before or during meals. Swallow whole w/ some liqd.
Contraindications
Hypersensitivity. Chronic intestinal disorders associated w/ marked malabsorption & indigestion; Roemheld's syndrome, major hernia, intestinal obstruction & ulcer; inflammatory bowel disease eg, ulcerative colitis & Crohn's disease, partial intestinal obstruction or predisposed intestinal or ileus obstruction. Severe renal impairment (CrCl <25 mL/min). Pregnancy & lactation. Childn & adolescent <18 yr.
Special Precautions
Monitor liver function during the 1st 6-12 mth of therapy.
Adverse Reactions
Flatulence, diarrhea & abdominal pain.
Drug Interactions
Sucrose & food containing sucrose; sulphonylurea, metformin or insulin. May affect digoxin bioavailability. Cholestyramine, intestinal adsorbents & digestive enzyme products should be avoided. Diuretics, corticosteroids, phenothiazines, thyroid prep, oestrogens, OCs, phenytoin, nicotinic acid, sympathomimetics, Ca-channel blocker & INH tend to produce hyperglycemia & may lead to loss of blood glucose control. Neomycin lead to an enhanced reduction of postprandial blood glucose & to an increase in the frequently & severity of GI adverse reactions.
MIMS Class
ATC Classification
A10BF01 - acarbose ; Belongs to the class of alpha glucosidase inhibitors. Used in the treatment of diabetes.
Presentation/Packing
Form
Eclid tab 50 mg
Packing/Price
5 × 10's (Rp1,500/tab, Rp75,000/boks)
Form
Eclid tab 100 mg
Packing/Price
5 × 10's (Rp120,000/boks, Rp2,400/tab)
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