Adult 18-64 yr RA
25 mg twice wkly. Alternatively, 50 mg once wkly. Psoriatic arthritis & ankylosing spondyilitis
25 mg SC twice wkly, alternatively, 50 mg once wkly. Plaque psoriasis
25 mg SC twice wkly, alternatively, 50 mg twice wkly may be used up to 12 wk followed, if necessary, by dose 25 mg twice wkly. Treatment should continue until remission is achieved for up to 24 wk. Discontinue in patients who show no response after 12 wk. Elderly ≥65 yr
Same as for adults 18-64 yr. Childn & adolescent (≥4 to <18 yr)
0.4 mg/kg SC (up to max of 25 mg/dose) twice wkly w/ interval 3-4 days between doses.