Fordica 500 XR

Fordica 500 XR





Concise Prescribing Info
Metformin HCl
Adjunct to diet & exercise or may be used concomitantly w/ sulfonylurea or insulin to improve glycemic control in patients w/ type 2 DM.
Dosage/Direction for Use
Initially 1 tab daily, may be increased up to a max of 2,000 mg/day in 500 mg-wkly increments.
Should be taken with food: Take w/ the evening meal.
Hypersensitivity. CV collapse, acute MI, septicemia. CHF, acute or chronic metabolic acidosis, diabetic keto­acidosis w/ or w/o coma. Patients undergoing radiologic studies w/ intravascular administra­tion of iodinated contrast materials. Renal disease.
Special Precautions
Lactic acidosis. Hypoxic states, surgical procedures, alcohol intake. Use of concomitant medications that may affect renal function or metformin disposition eg, cationic drugs. Temporarily discontinue treatment in patients if radiologic studies are planned. Change in clinical status of patients w/ previously controlled type 2 diabetes. Debilitated or malnourished patients. Hypoglycemia. Impaired renal & hepatic function. Pregnancy & lactation. Childn. Elderly.
Adverse Reactions
GI tract disorder (abdominal pain, constipation, abdominal distention, dyspepsia/heartburn, flatulence); dizziness, headache, upper resp tract infection, taste disturbance.
Drug Interactions
Enhanced absorption w/ nifedipine. Cationic medications that are excreted via renal tubular secretory system (eg, amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, vancomycin). Concomitant use w/ thiazide & other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, OCs, phenytoin, nicotinic acid, sympathomimetics, Ca channel blocking drugs, & INH may lead to loss of blood glucose control.
MIMS Class
Antidiabetic Agents
ATC Classification
A10BA02 - metformin ; Belongs to the class of biguanides. Used in the treatment of diabetes.
Fordica 500 XR caplet 500 mg
10 × 10's (Rp170,000/boks)
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