Initially 25 mg/kg daily, may be increased as soon as possible to reach the lowest therapeutic dose. Max: 60 mg/kg daily. Epilepsy Adult & childn ≥10 yr
Initially 15 mg/kg daily, increasing at 1-wk interval by 5-10 mg/kg daily until symptoms are controlled or side effects preclude further increases. Max: 60 mg/kg daily. Migraine prophylaxis
Recommended starting dose: 500 mg once daily for 1 wk, then increased to 1,000 mg once daily.