Frego Dosage/Direction for Use



Kalbe Farma
Full Prescribing Info
Dosage/Direction for Use
Recommended Dose: 10 mg daily. If adverse effects occur, reduce the dosage to 5 mg. Frego should be taken regularly once a day in the evening to avoid the sedative effect.
Migraine Prophylaxis: Starting Dose: Patients <65 years: 10 mg daily (at night); >65 years: 5 mg daily. If during this treatment, depressive, extrapyramidal or other unacceptable adverse experiences occur, administration should be discontinued. If after 2 months of this initial treatment, no significant improvement is observed, the administration should also be discontinued.
Maintenance Treatment: If patients are responding satisfactorily and if maintenance treatment is needed, the dose should be decreased to 5-day treatment a week and 2 days a week without Frego. Even if the prophylactic maintenance treatment is successful and well tolerated, it should be interrupted after 6 months and should be reinitiated only if the patients relapse.
Treatment of Cerebral and Peripheral Vestibular Disturbances: The same daily doses should be used as for migraine, but the starting treatment should not be given longer than needed for symptom control, which generally takes <2 months. However, if after 1 month for chronic vertigo or after 2 months for paroxysmal vertigo, nonsignificant improvement is observed, the administration should be discontinued.
Frego may be taken with or without food.
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