Ocular infections
Adult: As 0.3% eye drops: Instill 1-2 drops into affected eye(s) every 4 hours. Severe: Initially, 1-2 drops every 15-20 minutes, gradually reduce frequency as the infection is controlled. As 0.3% eye ointment: Apply a small amount (approx 1/2 inch ribbon) into affected eye(s) 2-3 times daily.
Child: Same as adult dose.
Child: Same as adult dose.
Otic/Aural
Otitis externa
Adult: As 0.3% ear drops: Instill 2-3 drops in the affected ear(s) 3-4 times a day and at night.
Child: Same as adult dose.
Child: Same as adult dose.
Parenteral
Susceptible infections
Adult: For severe infections: 3-5 mg/kg daily in divided doses 8 hourly for 7-10 days, by IM or slow IV inj over 2-3 minutes or IV infusion over no more than 20-30 minutes. Alternatively, initial dose of 5-7 mg/kg once daily via IV infusion, then adjust subsequent doses according to serum gentamicin concentration.
Child: <1 month 4-7 mg/kg daily; ≥1 month 4.5-7.5 mg/kg daily; ≥1 year 3-6 mg/kg daily. Doses are given as a single or in 2 divided doses.
Child: <1 month 4-7 mg/kg daily; ≥1 month 4.5-7.5 mg/kg daily; ≥1 year 3-6 mg/kg daily. Doses are given as a single or in 2 divided doses.
Parenteral
Bacterial meningitis, Ventriculitis
Adult: Initially, 1 mg daily via intrathecal or intraventricular inj, together with 1 mg/kg every 8 hours via IM inj.
Topical/Cutaneous
Skin infections
Adult: As 0.1% cream/ointment: Apply gently to cleansed affected area 3-4 times daily.
Child: Same as adult dose.
Child: Same as adult dose.