Post-exposure prophylaxis of hepatitis: acute exposure to blood containing HBsAg, perinatal exposure of infants born to HBsAg positive mothers, sexual exposure to an HBsAg positive person, household exposure to persons w/ acute HBV infection.
Dosage/Direction for Use
IMAcute exposure to blood containing HBsAg 0.06 mL/kg w/in 7 days of exposure. Prophylaxis of infant born to HBsAg & HBeAg positive mother 0.5 mL to be given w/in 12 hr of birth. Sexual exposure to an HBsAg positive person 0.06 mL/kg as single dose w/in 14 days of the last sexual contact. Household exposure to persons w/ acute HBV infectionInfant <12 mth 0.5 mL.
Prior systemic allergic reactions to human Ig, severe thrombocytopenia, coagulation disorder. Pregnancy.
Local pain & tenderness at the inj site, urticaria & angioedema, anaphylactic reactions.