Oral antidiabetic products, MAOIs, nonselective β-blocking agents, ACE inhibitors, salicylates, anabolic steroids & sulphonamides may reduce insulin requirement. OCs, thiazides, glucocorticoids, thyroid hormones, sympathomimetics, growth hormone & danazol may increase insulin requirements. β-blocking agents may mask symptoms of hypoglycemia & delay recovery from hypoglycemia. Octreotide/lanreotide may either increase or decrease insulin requirement. Alcohol may intensify or reduce hypoglycemic effect of insulin.