Epilepsy: Adults (>12 years): As adjunctive or monotherapy in the treatment of epilepsy, for partial seizures and generalized seizures, including tonic-clonic seizures and the seizures associated with Lennox-Gastaut Syndrome.
Children 2-12 years: As adjunctive therapy in the treatment of epilepsy, for partial seizures and generalized seizures including tonic-clonic seizures and the seizures associated with Lennox-Gastaut Syndrome. Initial monotherapy treatment in newly diagnosed paediatric patients is not recommended.
After epileptic control has been achieved during adjunctive therapy, concomitant antiepileptic drugs (AEDs) may be withdrawn and patients continued on Lamictal monotherapy.
Bipolar Disorder: Adults (≥18 years): Prevention of mood episodes in patients with bipolar disorder, predominantly by preventing depressive episodes.