Otilonium bromide is a quaternary salt of ammonium which has spasmolytic activity in GI and is widely used for irritable bowel syndrome therapy. This compound relaxes GI smooth muscle mainly through specific inhibition of calcium ion influx, namely on type L calcium channels. The effect of otilonium bromide spasmolytic, without showing the nature of the origin of the agonist, is more visible in the gastrointestinal smooth muscle than in the blood vessels or respiratory system.
Treatment of irritable bowel syndrome, symptomatic treatment of pain, and gastrointestinal disorders compared to blood vessels or the respiratory system.
Recommended dose: 1 tab 2-3 times daily, or as physician's recommendation.
It is recommended to initiate a symptomatic and supportive treatment if overdose occurred.
Hypersensitivity to the drug.
Patients with glaucoma, benign prostatic hyperplasia and pyloric stenosis. Pregnancy and lactation.
Reactions those have been reported are mild and non-specific, such as: headache, dizziness, nausea, fatigue, heartburn, and vertigo.
Store in the temperature below 30°C. Keep away from sunlight.
A03AB06 - otilonium bromide ; Belongs to the class of synthetic anticholinergics, quaternary ammonium compounds. Used in the treatment of functional bowel disorders.