Reduction of elevated total cholesterol & LDL in patient w/ primary hypercholesterolemia when response to diet lipid & cholesterol or other nonpharmacological measures has been inadequate. Reduction of elevated cholesterol levels in patient w/ combined hypercholesterolemia & hypertriglyceridemia when hypercholesterolemia is the abnormality of more concern.
Dosage/Direction for Use
Adult Initially 20 mg as single dose at night. Increase if needed after a 4-wk interval to max 80 mg/day to be taken in 2 divided doses.
Should be taken with food.
Active liver disease or unexplained persistent elevations of serum transaminase. Lactation.
Perform liver function test during therapy. Pregnancy.