Pharmacoclinical studies have not shown a complete antigonadotropic effect in all patients.
In some indications eg, uterine bleeding, amenorrhoea and dysmenorrhoea, it is essential to investigate the cause before starting treatment in order to ensure that the disorders are functional.
A clinical examination and if appropriate, additional tests should be done before starting treatment to confirm that there is no breast or uterine cancer (cervix, endometrium).
Administration of Lutenyl should be discontinued if any of the following occur: Ocular disorder (diplopia, acute visual impairment, retinal vascular lesions); clinical signs of arterial or venous thromboembolism; severe and unexplained headaches.
Medical follow-up is particularly advised in patients suffering from or having suffered from cardiovascular disease, unstable hypertension, diabetes or porphyria.
Effects on the Ability to Drive or Operate Machinery: No effects on ability to drive and use machines have been observed.
Use in lactation: Administration of Lutenyl is not advised during lactation due to the passage of steroids into breast milk.