Meronem

Meronem

meropenem

Manufacturer:

Pfizer
Concise Prescribing Info
Contents
Meropenem
Indications/Uses
Pneumonia including nosocomial pneumonias; UTI; intra-abdominal infections; gynecological infections eg, endometritis, skin & skin structure infections; meningitis; septicemia; empiric treatment in adults w/ febrile neutropenia. Polymicrobial infections.
Dosage/Direction for Use
IV bolus inj over approx 5 min or IV infusion over approx 15-30 min. Adult Pneumonia, UTI, gynecological infections eg, endometritis, skin & skin structure infections 500 mg IV 8 hrly. Nosocomial pneumonias, peritonitis, presumed infections in neutropenic patients, septicemia 1 g IV 8 hrly. Meningitis 2 g 8 hrly. Childn >3 mth-12 yr 10-20 mg/kg 8 hrly, >50 kg Adult dose. Meningitis 40 mg/kg 8 hrly.
Contraindications
Special Precautions
History of hypersensitivity to carbapenems, penicillins or other β-lactams. Overgrowth of nonsusceptible organisms may occur. Use in infections caused by methicillin resistant staphylococci. Monitor levels of transaminase & bilirubin in patients w/ hepatic disease. History of GI complaints, particularly colitis. Monitor liver function. A positive direct or indirect Coombs test may develop. May impair ability to drive or operate machinery. Pregnancy & lactation. Infant <3 mth.
Adverse Reactions
Thrombocytopenia, headache, diarrhea, vomiting, nausea, increased alanine, aspartate aminotransferase, blood alkaline phosphatase, blood lactate dehydrogenase, γ-glutamyltransferase, rash, pruritus, inflammation, pain.
Drug Interactions
Probenecid inhibits renal excretion. Decreased valproic acid blood levels.
MIMS Class
ATC Classification
J01DH02 - meropenem ; Belongs to the class of carbapenems. Used in the systemic treatment of infections.
Presentation/Packing
Form
Meronem IV inj 500 mg
Packing/Price
(vial) 10 × 1's (Rp3,569,573/boks)
Form
Meronem IV inj 1 g
Packing/Price
(vial) 10 × 1's (Rp6,338,834/boks)
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