Adult Initially 4-48 mg/day as a single or in divided doses. Multiple sclerosis 160 mg/day for 1 wk, followed by 64 mg every other day for 1 mth. ChildnAdrenocortical insufficiency 0.117 mg/kg/day in 3 divided doses. Other indications 0.417-0.167 mg/kg/day in 3-4 divided doses.
Should be taken with food.
Systemic fungal infections. Prolonged use in duodenal & peptic ulcers, severe osteoporosis, history of psychoses, herpes; recent vaccination.