Each capsule contains: Mecobalamin 500 µg.
Pharmacology: Mecobalamin is a kind of endogenous coenzyme of vitamin B12 which is neurologically active.
Mecobalamin is well transported to nerve cell organelles and promotes nucleic acid, protein and lipid synthesis. Mecobalamin promotes axonal transport, axonal regeneration and myelination (phospolipid synthesis).
Mecobalamin restores delayed synaptic transmission and diminished neurotransmitters to normal.
The usual adult dosage: 1 capsule, 3 times daily.
The dosage may be adjusted depending on the symptoms and patient's age.
Patients known hypersensitive to any component of a vitamin B12-containing product or to other components in this drug.
The treatment of mecobalamin should be discontinued if there is no response after several months.
The prolonged use of larger doses of mecobalamin is not recommended for patients whose occupation expose or related to mercury or mercury-containing substances.
Use with caution in patients with cardiovascular disease, lung disease and hypertension.
Mecobalamin is hygroscopic, therefore capsules should be stored in an airtight container and protected from moisture and light.
anorexia, nausea, vomiting and diarrhea.
Metformin, H2 receptor antagonists (cimetidine, ranitidine etc), aminoglycosides, colchicine, aminosalicyclic acid, anticonvulsants and alcohol may decrease vitamin B12 absorption.
Avoid mecobalamin use with chloramphenicol.
STORE AT TEMPERATURE BELOW 30°C. PROTECT FROM LIGHT.
B03BA05 - mecobalamin ; Belongs to the class of vitamin B12 (cyanocobalamin and analogues). Used in the treatment of anemia.