Patients with known hypersensitivity to any component of the infusions or other quinolones.
Pregnancy and lactation.
Patients below 18 years of age.
Patients with a history of tendon disease/disorder related to quinolones treatment.
Patients with congenital or documented acquired QT prolongation.
Patients with electrolyte disturbances, particularly in hypokalemia.
Patients with clinically relevant bradycardia.
Patients with clinically relevant heart failure with reduced left-ventricular ejection fraction.
Patients with previous history of symptomatic arrhythmias.