Natexam

Natexam

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Full Prescribing Info
Contents
Indapamide, amlodipine.
Description
Each 1.5/5 mg MR tab contains 1.5 mg indapamide and 5 mg amlodipine.
Each 1.5/10 mg MR tab contains 1.5 mg indapamide and 10 mg amlodipine.
Indications/Uses
As substitution therapy for the treatment of essential hypertension in patients already controlled with indapamide and amlodipine given concurrently at the same dose level.
Dosage/Direction for Use
1 tab/day, preferably to be taken in the morning.
Contraindications
Hypersensitivity to the active substances, severe renal failure, hepatic encephalopathy, hypokalaemia, lactation, severe hypotension, shock, obstruction of the outflow tract of the left ventricle (e.g. high grade aortic stenosis), haemodynamically unstable heart failure after acute myocardial infarction.
Special Precautions
Hypertensive crisis, water and electrolyte balance, blood glucose, cardiac failure, renal function, uric acid, hepatic function, older people, athletes, excipients.
Use In Pregnancy & Lactation
Natexam is contraindicated in lactating women.
Adverse Reactions
Somnolence, dizziness, headache, palpitations, flushing, abdominal pain, nausea, ankle swelling, oedema and fatigue.
Drug Interactions
Lithium, Torsades de pointes-inducing medicines, NSAIDs, ACE inhibitors, other compounds causing hypokalemia, digitalis prep, baclofen, allopurinol, K-sparing diuretics, metformin, iodinated contrast media, imipramine-like antidepressants, Ca, ciclosporin, tacrolimus, corticosteroid, tetracosactide.
ATC Classification
C08GA02 - amlodipine and diuretics ; Belongs to the class of calcium-channel blockers in combination with diuretics. Used in the treatment of cardiovascular diseases.
Presentation/Packing
1.5/5 mg MR tab 1's. 1.5/10 mg MR tab 1's.
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