Pantozol 40

Pantozol 40

pantoprazole

Manufacturer:

Takeda
Concise Prescribing Info
Contents
Pantoprazole
Indications/Uses
In combination w/ 2 appropriate antibiotic for eradication of H. pylori in patients w/ peptic ulcer. Duodenal ulcer, gastric ulcer, moderate & severe reflux esophagitis. Zollinger-Ellison syndrome & other pathological hypersecretory conditions.
Dosage/Direction for Use
H. pylori eradication 1 tab w/ 1,000 mg amoxicillin & 500 mg clarithromycin or 1 tab w/ 500 mg metronidazole & 500 mg clarithromycin or 1 tab w/ 1,000 mg amoxicillin & 500 mg metronidazole. To be taken twice daily. Monotherapy for treatment of gastric & duodenal ulcer & reflux esophagitis 1 tab daily. Dose may be doubled especially if no response. Long-term management of Zollinger-Ellison syndrome & other pathological hypersecretory conditions Initially 80 mg daily. Titrate dosage up or down as needed. Severe liver impairment Reduce dose to 1 tab every other day. Elderly or patient w/ impaired renal function Do not exceed 40 mg daily except in eradication of H. pylori.
Administration
Should be taken on an empty stomach: Take 1 hr before breakfast. Swallow whole w/ water, do not chew/crush. In combination therapy for eradication of H. pylori, the 2nd 40 mg tab should be taken before the evening meal.
Contraindications
Hypersensitivity. In combination treatment for eradication of H. pylori in patients w/ moderate to severe hepatic/renal dysfunction.
Special Precautions
Not for mild GI complaints eg, nervous dyspepsia. In patients w/ Zollinger-Ellison syndrome & other hypersecretory conditions requiring long-term treatment may reduce absorption of vit B12 due to hypo- or achlorhydria. Exclude possibility of malignancy of gastric ulcer or malignant disease of the esophagus prior to treatment. Pregnancy & lactation. Childn.
Adverse Reactions
Nausea, vomiting, diarrhoea, constipation, dry mouth, abdominal pain, flatulence; increased liver enzymes; headache, dizziness; allergic reactions eg, pruritus & skin rash.
Drug Interactions
May reduce absorption of ketoconazole. May reduce absorption of vit B12. Monitor prothrombin time/INR in patients also taking coumarin.
ATC Classification
A02BC02 - pantoprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).
Presentation/Packing
Form
Pantozol 40 gastro-resistant tab 40 mg
Packing/Price
1 × 7's (Rp132,000.00/boks)
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