Recommended only if PO is not appropriate. Not for mild GI complaints eg, nervous dyspepsia. Exclude malignancy in the presence of any alarm symptoms eg, significant unintentional wt loss, recurrent vomiting, dysphagia, haematemesis, anaemia or melaena & when gastric ulcer is suspected or present. Diagnosis of reflux esophagitis should be confirmed by endoscopy. Monitor liver enzymes in patients w/ severe liver impairment. Discontinue therapy in case of rise of liver enzymes. Pregnancy & lactation.