Pantozol IV

Pantozol IV

pantoprazole

Manufacturer:

Takeda
Concise Prescribing Info
Contents
Pantoprazole
Indications/Uses
Duodenal, gastric ulcer; moderate & severe cases of inflammation of the oesophagus (reflux esophagitis). Pathological hypersecretory condition associated w/ Zollinger-Ellison syndrome & other neoplastic conditions.
Dosage/Direction for Use
IV Duodenal, gastric ulcer, moderate & severe reflux esophagitis 40 mg/day. Long-term management of Zollinger-Ellison syndrome & other pathological hypersecretory conditions Initially 80 mg daily then titrate up/down as needed. Doses >80 mg/day should be divided & given twice daily. A temporary increase of dose >160 mg should not be applied longer than required for adequate acid control. In case rapid acid control is required, starting dose of 2-80 mg pantoprazole is sufficient to manage a decrease of acid output to target range.
Special Precautions
Recommended only if PO is not appropriate. Not for mild GI complaints eg, nervous dyspepsia. Exclude malignancy in the presence of any alarm symptoms eg, significant unintentional wt loss, recurrent vomiting, dysphagia, haematemesis, anaemia or melaena & when gastric ulcer is suspected or present. Diagnosis of reflux esophagitis should be confirmed by endoscopy. Monitor liver enzymes in patients w/ severe liver impairment. Discontinue therapy in case of rise of liver enzymes. Pregnancy & lactation.
Adverse Reactions
Thrombophlebitis & inj site reactions.
Drug Interactions
Changes in absorption w/ ketoconazole. Monitor prothrombin time/INR after initiation, termination or during irregular use w/ coumarin anticoagulants.
ATC Classification
A02BC02 - pantoprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).
Presentation/Packing
Form
Pantozol IV inj 40 mg
Packing/Price
(vial) 1's (Rp168,200.00/boks)
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