Purgatix Oral

Per 5 mL Na phosphate monobasic monohydrate 2.4 g, dibasic Na phosphate heptahydrate 0.9 g

Part of bowel cleansing procedure prior to abdominal X-ray, colonoscopy or GI surgery.

Dissolve 1 bottle of soln w/ 720 mL of water taken into 2 divided doses.

Should be taken on an empty stomach: Best taken at least 30 min before meal. Dilute dosage w/ ½ glass (120 mL) of cool water. Drink, then follow w/ 1 glass (240 mL) of cool water.

Hypersensitivity. Patients w/ faecal impaction, paralytic ileus, intestinal obstruction, hypomotility, Hirschsprung's disease, imperforate anus, congestive heart disease, ascites, decreased kidney function & failure & potential for fluid/electrolyte disturbances in previous condition. Patients w/ risk of dehydration due to changes in taste &/or poor fluid intake. Patients w/ known or suspected GI obstruction or poor intestinal motility; inflammatory bowel disease; nausea, vomiting or abdominal pain. Childn <15 yr w/ risk of dehydration.

Dose >45 mL may result to serious electrolyte disturbances eg, hypernatremia, hypokalemia, hyperphosphatemia, hypocalcemia, dehydration, metabolic acidosis, kidney failure, tetany & death. Patients are required to fast & only consume clear fluids for intake of breakfast, lunch & dinner one day prior to the procedure. Monitor fluid intake during treatment. Diuretic. Diabetes. Patients w/ heart problems, acute MI, unstable angina, preexisting electrolyte disorders, or patients who have been using drugs that can prolong QT intervals, ulcerative colitis, DM, reflux esophagitis, disturbed swallowing reflexes, decreased consciousness or which may cause regurgitation or aspiration. Severe renal impairment. Elderly & debilitated patients, & patients w/ colostomy or on low Na diet.

Dehydration or electrolyte disorders eg, hyperphosphatemia, hypocalcemia, hypokalemia, hypernatremia & acidosis; nausea, vomiting, abdominal pain, bloating & diarrhea; weakness, chills, headaches, dizziness; allergic reactions w/ or w/o redness, fatigue & GI cramps.

Ca channel blockers, diuretics, lithium or other medications that can affect electrolyte levels eg, hyperphosphate, hypocalcemia, hypokalemia, hypernatremia dehydration & acidosis can occur. Reduced efficacy w/ OCs, anti-epilepsy, antidiabetic, or antibiotics. Concomitant administration w/ intestinal cleansers polyethylene glycol may be dangerous & not recommended.

Laxatives, Purgatives

A06AD17 - sodium phosphate ; Belongs to the class of osmotically acting laxatives.

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