Purgatix Oral

Purgatix Oral

Manufacturer:

Meprofarm
Concise Prescribing Info
Contents
Per 5 mL Na phosphate monobasic monohydrate 2.4 g, dibasic Na phosphate heptahydrate 0.9 g
Indications/Uses
Part of bowel cleansing procedure prior to abdominal X-ray, colonoscopy or GI surgery.
Dosage/Direction for Use
Dissolve 1 bottle of soln w/ 720 mL of water taken into 2 divided doses.
Administration
Should be taken on an empty stomach: Best taken at least 30 min before meal. Dilute dosage w/ ½ glass (120 mL) of cool water. Drink, then follow w/ 1 glass (240 mL) of cool water.
Contraindications
Hypersensitivity. Patients w/ faecal impaction, paralytic ileus, intestinal obstruction, hypomotility, Hirschsprung's disease, imperforate anus, congestive heart disease, ascites, decreased kidney function & failure & potential for fluid/electrolyte disturbances in previous condition. Patients w/ risk of dehydration due to changes in taste &/or poor fluid intake. Patients w/ known or suspected GI obstruction or poor intestinal motility; inflammatory bowel disease; nausea, vomiting or abdominal pain. Childn <15 yr w/ risk of dehydration.
Special Precautions
Dose >45 mL may result to serious electrolyte disturbances eg, hypernatremia, hypokalemia, hyperphosphatemia, hypocalcemia, dehydration, metabolic acidosis, kidney failure, tetany & death. Patients are required to fast & only consume clear fluids for intake of breakfast, lunch & dinner one day prior to the procedure. Monitor fluid intake during treatment. Diuretic. Diabetes. Patients w/ heart problems, acute MI, unstable angina, preexisting electrolyte disorders, or patients who have been using drugs that can prolong QT intervals, ulcerative colitis, DM, reflux esophagitis, disturbed swallowing reflexes, decreased consciousness or which may cause regurgitation or aspiration. Severe renal impairment. Elderly & debilitated patients, & patients w/ colostomy or on low Na diet.
Adverse Reactions
Dehydration or electrolyte disorders eg, hyperphosphatemia, hypocalcemia, hypokalemia, hypernatremia & acidosis; nausea, vomiting, abdominal pain, bloating & diarrhea; weakness, chills, headaches, dizziness; allergic reactions w/ or w/o redness, fatigue & GI cramps.
Drug Interactions
Ca channel blockers, diuretics, lithium or other medications that can affect electrolyte levels eg, hyperphosphate, hypocalcemia, hypokalemia, hypernatremia dehydration & acidosis can occur. Reduced efficacy w/ OCs, anti-epilepsy, antidiabetic, or antibiotics. Concomitant administration w/ intestinal cleansers polyethylene glycol may be dangerous & not recommended.
ATC Classification
A06AD17 - sodium phosphate ; Belongs to the class of osmotically acting laxatives.
Presentation/Packing
Form
Purgatix Oral soln
Packing/Price
45 mL x 1's
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