There are currently no known drug interactions associated with the use of topical Minoxidil or Finasteride administration. Although it has not been clinically demonstrated, there exist the possibility of Minoxidil potentiating orthostatic hypotension in patients concurrently taking Guanethidine.
This product should not be used together with other topical drug that used in scalp. Topical drugs like corticosteroids, tretinoin, dithranol or petrolatum can change stratum corneum which leads to increase the absorption of Minoxidil simultaneously. Although it has not been proven clinically, theoretically there is possibility of absorption of Minoxidil which has the potential to cause orthostatic hypotension due to peripheral vasodilation.