Sibelium-5/Sibelium-10 Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info Full Prescribing Info Contents Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Flunarizine

Indications/Uses

Prevention of migraine. Treatment & prevention of vestibular, cerebral & peripheral circulatory disorders eg, dizziness, tinnitus, vertigo; difficulty concentrating & confusion; memory disorders, sleep rhythms & irritability; seizures when walking & lying down, paresthesia, cold extremities & tropic disorders, along w/ diet, smoking cessation & exercise.

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Dosage/Direction for Use

Prevention of migraine Prevalent dose: Patient >64 yr 5 mg once daily at night, 18-64 yr 10 mg once daily at night. Maintenance dose: Same daily dose for 5 days, followed by 2 consecutive days w/ no therapy. Repeat cycle wkly for 6 mth & may be continued if recurrence occurs. Treatment & prevention of vestibular, cerebral & peripheral circulatory disorders Patient >64 yr 5 mg once daily at night, 18-64 yr 10 mg once daily at night until symptoms disappear.

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Overdosage

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Administration

May be taken with or without food.

Contraindications

Hypersensitivity. History of depression or symptoms of Parkinson's disease or other extrapyramidal abnormalities.

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Special Precautions

May cause extrapyramidal symptoms, depression & occurrence of parkinsonism. Hypotension. Fatigue. May impair ability to drive & use machines. Pregnancy & lactation. Elderly.

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Adverse Reactions

Hypersensitivity, insomnia, anxiety, nervous system disorder, hypotension, flushing, GI disorder, muscle rigidity, skin & SC tissue disorder, galactorrhea.

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Drug Interactions

Severe drowsiness w/ alcohol, hypnotics & tranquilizer drugs. Galactorrhea w/ OC drugs during the first 2 mth.

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Storage

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Action

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MIMS Class

Peripheral Vasodilators & Cerebral Activators / Antiemetics / Antimigraine Preparations

ATC Classification

N07CA03 - flunarizine ; Belongs to the class of antivertigo preparations.

Regulatory Classification

Presentation/Packing

Form

Sibelium-10 tab 10 mg

Packing/Price

10 × 10's (Rp1,316,785/boks)

Form

Sibelium-5 tab 5 mg

Packing/Price

10 × 10's (Rp790,071/boks)

Sibelium-5/Sibelium-10

flunarizine

Manufacturer:

Johnson & Johnson