Simdrol-4

Simdrol-4

methylprednisolone

Manufacturer:

Simex
Concise Prescribing Info
Contents
Methylprednisolone
Indications/Uses
Collagen & allergic disease, herpetiform & exfoliative dermatitis, Stevens-Johnson syndrome, psoriasis; allergic conjunctivitis, keratitis, optic neuritis, iritis; leukemia & lymphoma in adult patients & acute leukemia in childn; ulcerative colitis & Crohn's disease; nephrotic syndrome; rejection of organ transplant; adrenocortical insufficiencies; idiopathic thrombocytopenic purpura in adults; rheumatic disease.
Dosage/Direction for Use
Adult 4-48 mg daily. Multiple sclerosis 160 mg daily for 1 wk, followed by 64 mg daily for 1 mth. Alternate-Day Therapy Regimen: 1 tab every 2 days.
Administration
Should be taken with food.
Contraindications
Hypersensitivity. TB, systemic fungal infections, vaccinia or varicella, herpes simplex keratitis, peptic ulcer, Cushing's syndrome, acute psychosis, recent vaccination.
Special Precautions
Patients receiving corticosteroid therapy or in stressful conditions. May mask any signs of infections. Avoid vaccination during treatment. Prolonged use. Avoid abrupt w/drawal. Pregnancy & lactation. Infants, childn.
Adverse Reactions
Prolonged use may cause moon face, fatty deposits in some body parts, muscle weakness, HTN, osteoporosis, reduced glucose tolerance, impaired sex hormone secretion, striae, petechiae, acne, edema, hypokalemia, atrophy of adrenal cortex, vasculitis, peptic ulcer, reduced body immunity, delayed wound healing, growth retardation in childn, glaucoma, cataract, thrombosis, psychosis, allergic reactions, CHF, Na retention.
Drug Interactions
Cardiac glycosides, cyclosporine, phenobarb, phenytoin, rifampicin, troleandomycin, ketoconazole, anticoagulant, ASA, neuromuscular blocking agent (eg, pancuronium), insulin, antihypertensives, diuretic antagonist, acetazolamide, loop & thiazide diuretic, carbenoxolone.
ATC Classification
H02AB04 - methylprednisolone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Presentation/Packing
Form
Simdrol-4 tab 4 mg
Packing/Price
10 × 10's
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