Spedifen Use In Pregnancy & Lactation



Full Prescribing Info
Use In Pregnancy & Lactation
Use in pregnancy: Although studies performed in animals did not show evidence of teratogenic action, it is recommended to avoid ibuprofen administration during the 1st months of pregnancy, as these studies are not predictive of a certain human response. Similarly, owing to prostaglandin synthesis inhibition and some cases, to fetal cardiovascular effects (closing of Botallo's duct), it is recommended not to administer ibuprofen during the last months of pregnancy, except in cases of strict necessity.
Use in lactation: Being proved the passage of ibuprofen into the mother's milk, its administration is not recommended during the lactation period.
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