SPORETIK is generally well tolerated.
The majority of adverse reactions were mild and self-limiting in nature.
Gastrointestinal disturbances: Gastrointestinal disturbance is the most frequent adverse reactions which occured, such as diarrhoea, abdominal pain, nausea, vomiting, dyspepsia, flatulence, pseudomembraneous colitis, anorexia, heartburn, constipation.
Hypersensitivity reactions: Skin rash, urticaria, erythema, pruritus.
Hepatic: Transient elevations in SGPT, SGOT and alkaline phosphatase.
Haematologic: Transient thrombocytopenia, leukopenia and eosinophilia may occasionally occur.
Central nervous system: Headache, dizziness.
Others: Shock, genital pruritus, vaginitis, candidiasis, toxic epidermal necrolysis, superinfection, renal dysfunction, toxic nephropathy, hepatic dysfunction, haemorrhage and colitis.
Abnormal laboratory tests: Positive direct Coombs test, neutropenia, agranulocytosis, elevated bilirubin and LDH.