Starcef Adverse Reactions



Dexa Medica
Full Prescribing Info
Adverse Reactions
Shock: Adequate caution should be exercised since shock symptoms may sometimes occur. If any related signs or symptoms eg, dysphoria, oral cavity discomfort, stridor, dizziness, abnormal urge to defecate, tinnitus or diaphoresis occur, Starcef must be discontinued immediately.
Hypersensitivity: If signs of hypersensitivity reactions eg, rash, urticaria, erythema, pruritus or fever occur, the administration of Starcef should be discontinued and appropriate measures should be taken.
Hematologic: Granulocytopenia or eosinophilia may occur rarely. Sometimes, thrombocytopenia may also occur. The use of Starcef should be discontinued if any of such disorders is found. It has been reported that hemolytic anemia has occurred in the use of other cephems.
Hepatic: Infrequently, an increase in GOT, GPT or alkaline phosphatase may occur.
Renal: Periodic monitoring of renal function is recommended since serious renal impairment eg, renal insufficiency may sometimes occur. If any of such abnormalities is found, Starcef should be discontinued and appropriate measures should be taken.
Digestive: In rare instances, a serious colitis eg, pseudomembranous colitis, manifested by blood in stools may occur. Abdominal pain or continuous diarrhea requires appropriate measures; infrequently, vomiting, diarrhea, abdominal pain, stomach discomfort, heartburn or anorexia, nausea, feeling of fullness or constipation may occur.
Respiratory: In rare instances, interstitial pneumonia or PIE syndrome, manifested by fever, cough, dyspnea, abnormal chest x-ray or eosinophilia may occur. If any such symptoms occur, Starcef should be immediately discontinued and appropriate measures eg, administration of adrenocortical hormones should be taken.
Alteration in Bacterial Flora: Stomatitis or candidiasis may occur rarely.
Vitamin Deficiencies: Vitamin K deficiencies eg, hypoprothrombinemia or bleeding tendencies or vitamin B group deficiencies (eg, glossitis, stomatitis, anorexia or neuritis) may occur infrequently.
Others: Headache or dizziness may occur rarely. In studies where infant rats were given 1000 mg/kg body weight/day orally, a reduction in spermatogenesis was reported.
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