Capsule: Adults and Children Weighing ≥30 kg: Recommended Daily Dose: 50-100 mg (potency) of cefixime given orally twice a day.
Dosage should be adjusted according to age, body weight and condition of the patients.
Severe Infections: The dosage may be increased up to 200 mg (potency), given twice a day.
Suspension: Children: Usual Daily Dose: 1.5-3 mg (potency)/kg body weight given orally twice a day. Dosage should be adjusted according to the condition of the patients.
Severe Infections: The dosage may be increased up to 6 mg (potency)/kg body weight given twice a day.
Otitis Media: Treat with Starcef suspension.
Clinical studies of otitis media treated with cefixime suspension resulted in higher peak plasma concentration than the tablet when administered at the same dose. Therefore, suspension should not be substituted with tablet in the treatment of otitis media.
Patients with impaired renal function need a dosage adjustment depending on the degree of impairment. Recommended Dosage: 75% of the standard dosage (ie, 300 mg a day) if creatinine clearance is between 21 and 60 mL/min or for patients on renal hemodialysis and 50% of the standard dosage (ie, 200 mg a day) if creatinine clearance is <20 mL/min or for patients on continuous ambulatory dialysis.
Reconstitution of Dry Syrup: Add 10 mL of water, shake for 30 sec. Add 10 mL more of water and shake again for 30 sec.