General: Caution should be exercised since hypersensitivity reactions eg, shock may occur.
Starcef should not be administered in patients who may still be treated with other antibiotics. If necessary, it should be administered with caution. Patients with history of hypersensitivity to any ingredient of Starcef or any other cephem antibiotics.
Cefixime should be administered carefully to the following patients: Patients with a history of hypersensitivity to penicillin.
Patients with a personal or familial history to various forms of allergy eg, bronchial asthma, rash and urticaria.
Patients with serious renal dysfunction.
Patients with poor oral nutrition, those receiving parenteral nutrition, the elderly or patients in debilitated state. These patients must be monitored as vitamin K deficiency symptoms may develop.
Use in pregnancy: Safety during pregnancy has not been established.
Starcef should be administered to pregnant or those suspected of being pregnant only if the expected therapeutic benefits are thought to outweigh any possible risk.
Use in lactation: It is not known whether cefixime is excreted in human milk, therefore, nursing must be temporarily discontinued during treatment with Starcef.
Use in children: Safety and efficacy of cefixime administration in children <6 months has not been established (including newborns and prematures).