Ticlopidine is a blood-thinning medicine. It prevents special cells in the blood from sticking to each other. This reduces the risk of harmful blood clots forming in your body. Blood clots that form in a blood vessel inside the brain or in a vessel leading to the brain can cause a stroke.
This medicine is used to reduce the risk of stroke in people who have a high risk of getting them. This includes people who have had a stroke before and are at risk of getting another stroke and people with medical conditions that may increase their chances of getting a stroke.
Ticlopidine is also used together with other medicines to prevent blood clots in people who have had stents inserted into their heart arteries.
This medicine may also be used to treat other conditions such as blood circulation problems in the leg or heart disease.
Take Ticlopidine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
This medicine should be taken with food. This will help lessen any stomach discomfort that Ticlopidine may cause. Try to take it at the same time each day.
This medicine must be taken regularly for it to be effective. Continue taking Ticlopidine even when you feel better. Do not stop taking it unless instructed by your doctor.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal schedule.
DO NOT double a dose under any circumstances.
If you often forget to take your medicine, let your doctor and pharmacist know.
Alert your doctor if you have any of the following conditions:
- blood disorders
- stomach ulcers, especially if you have ever bled from a stomach ulcer
- severe liver disease
as Ticlopidine may not be suitable for you.
Inform your doctor if you have kidney disease.
Let your doctor know if you are pregnant or breastfeeding.
As Ticlopidine may increase the length of time needed to stop bleeding, alert your doctor if you have any recent injury, surgery or condition that puts you at a higher risk of bleeding.
If you are going for an operation, including minor operations and dental work, inform your doctor or dentist that you are taking this medicine.
Do not participate in activities in which you may fall or get injured, such as contact sports. Alert your doctor if you get any unusual bruising (large bruises or several bruises) or bleeding that takes a long time to stop (for example, too much bleeding when you floss or brush your teeth).
For as long as you are taking this medicine, you may need to have regular blood tests (e.g. blood cholesterol levels) to check your body's response to the medicine. Your doctor will advise you about how often you need to have blood tests.
Ticlopidine may cause any of the following side effects: stomach upset, diarrhoea, nausea, indigestion and itchy rashes.
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor if you are taking any of these medicines:
- other blood-thinning medicines e.g. warfarin, aspirin and clopidogrel
- theophylline (medicine for asthma)
- cimetidine (a gastric medicine)
- digoxin (medicine for heart disease)
- propranolol (medicine for high blood pressure)
- medicines for epilepsy (seizures or fits) e.g. phenobarbital, phenytoin
- painkillers known as NSAIDs, for example, diclofenac, ibuprofen, naproxen, mefenamic acid
This list does not include all medicines that may interact with Ticlopidine.
Do not take antacids together with this medicine. If you must take antacids, take them at least 1 hour before or 2 hours after you have taken Ticlopidine. Antacids can reduce the effectiveness of this medicine when taken together.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.