Toremifene - oral

Patient Medicine Information
Why do I need this medicine?
Toremifene is used to treat metastatic breast cancer (tumour that has spread from the place it first started to another parts of the body). It is given to those who no longer have menstrual periods.

This medicine may be used to treat other conditions as decided by your doctor.
How do I take this medicine?
Take Toremifene exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take this medicine with or without food. Try to take it at the same time each day.

Toremifene must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor or pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:

- heart rhythm disorder
- abnormal growth or thickening of the lining of the uterus
- severe blood clot disorder
- severe liver disease
- heart disease
- low potassium level in the blood
- low magnesium level in the blood
as Toremifene may not be suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you the following conditions:

- liver disease
- blood clot disorder

Let your doctor know if you are pregnant or breastfeeding.

For as long as you are taking Toremifene, you will need to have regular tests for blood count, liver function, calcium and magnesium concentration and an ECG (a recording of electrical activity of the heart) to check your body's response to the medicine. Your doctor will advise you about how often you will need to have these tests.
What side effects could I experience?
Toremifene may cause dizziness or some problems with your eyesight. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.

Other side effects include any of the following: excessive sweating, hot flushes, nausea and unusual vaginal discharge.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:

- blood-thinning medicines e.g. warfarin
- medicines for epilepsy (fits or seizures) e.g. carbamazepine, phenytoin, phenobarbital
- antibiotics e.g. erythromycin, moxifloxacin, pentamidine
- medicines for malaria e.g. halofantrine
- medicines for fungal infections e.g. ketoconazole
- medicines for tuberculosis (TB) e.g. rifampicin
- medicines for irregular or abnormal heartbeat e.g. quinidine, hydroquinidine, disopyramide, amiodarone, sotalol
- medicines for mood disorder e.g. pimozide, sertindole, haloperidol, sultopride
- medicines for allergies e.g. terfenadine, astemizole, mizolastine

This list does not include all medicines that may interact with Toremifene.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.

Avoid excessive consumption (more than 1 litre a day) of grapefruit juice.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

As this is a cancer medicine, always return any unused or expired tablets to the clinic, hospital or pharmacy for disposal. Do not throw it away in the household waste.
This information is independently developed by MIMS based on toremifene - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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