Tripenem Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Meropenem

Indications/Uses

Pneumonia, nosocomial pneumonia, UTI, intra-abdominal, gynaecological, skin & skin structure, bone & joint infections. Meningitis, septicemia, endocarditis. Empiric treatment for suspected infection in adult patient w/ febrile neutropenia (as a mono- or combined therapy w/ antiviral or antifungal agents).

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Dosage/Direction for Use

Adult Pneumonia, UTI, gynaecological infection (eg, endometritis), skin & skin structure infection 500 mg IV 8 hrly. Nosocomial pneumonia, peritonitis, presumed infection in patient w/ neutropenia, septicemia 1 g IV 8 hrly. Childn 3 mth-12 yr 10-20 mg/kg 8 hrly, childn >50 kg Adult dose. Meningitis 2 g 8 hrly. Renal impairment CrCl 26-50 mL/min 1 unit dose 12 hrly, 10-25 mL/min ½ unit dose 12 hrly, <10 mL/min ½ unit dose 24 hrly.

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Overdosage

View Tripenem overdosage for action to be taken in the event of an overdose.

Contraindications

History of hypersensitivity.

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Special Precautions

May cause overgrowth of nonsensitive microorganisms; hepatic impairment; methicillin-resistant staphylococci-caused infections. Co-administration w/ nephrotoxic drugs. CNS disorders, bacterial meningitis. Pregnancy & lactation. Childn <3 mth.

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Adverse Reactions

Inflammation, thrombophlebitis, pain at inj site; abdominal pain, nausea, vomiting, diarrhea, pseudomembranous colitis; reversible thrombocytopenia, leucopenia, neutropenia, increased serum conc eg, bilirubin, transaminases, alkaline phosphatase, lactase dehydrogenase alone or combination; headache, paresthesia; oral & vag candidosis.

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Drug Interactions

Probenecid, valproic acid.

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Storage

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Description

View Tripenem description for details of the chemical structure and excipients (inactive components).

Action

View Tripenem mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Other Beta-Lactams

ATC Classification

J01DH02 - meropenem ; Belongs to the class of carbapenems. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Tripenem inj 0.5 g

Packing/Price

1's (Rp198,000/vial)

Form

Tripenem inj 1 g

Packing/Price

1's (Rp365,500/vial)

Tripenem

meropenem

Manufacturer:

Dexa Medica