This drug may cause dizziness, drowsiness or weakness, if affected, do not drive or operate machinery.
Increased sedation w/ CNS depressants (e.g. barbiturates, hypnotics, opioid analgesics, anxiolytics, sedatives and antipsychotics). Increased antimuscarinic side effects w/ other antimuscarinic drugs (e.g. atropine, TCA and MAOI). May mask signs of ototoxicity caused by aminoglycosides.
Increased sedation w/ alcohol.
Description: Triprolidine blocks the action of endogenous histamine by binding to H1 receptor. It is useful for the prevention and suppression of the signs and symptoms of allergic rhinitis and other upper resp allergies. Pharmacokinetics: Absorption: Time to peak plasma concentration: Approx 2 hr. Distribution: Distributed into breast milk. Metabolism: Metabolised hepatically to carboxylated derivative. Excretion: Via urine, approx 1% as unchanged drug. Elimination half-life: Approx 2 hr.
R06AX07 - triprolidine ; Belongs to the class of other antihistamines for systemic use.
Anon. Triprolidine Hydrochloride. AHFS Clinical Drug Information [online]. Bethesda, MD. American Society of Health-System Pharmacists, Inc. https://www.ahfscdi.com. Accessed 11/07/2016.Anon. Triprolidine. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 11/07/2016.Buckingham R (ed). Interactions of Antihistamines. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 12/07/2016.Buckingham R (ed). Triprolidine Hydrochloride. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 11/07/2016.McEvoy GK, Snow EK, Miller J et al (eds). Antihistamines General Statement. AHFS Drug Information (AHFS DI) [online]. American Society of Health-System Pharmacists (ASHP). https://www.medicinescomplete.com. Accessed 12/07/2016.Vanahist PD Liquid (GM Pharmaceuticals, Inc). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 21/04/2014.