Truvaz

Truvaz

atorvastatin

Manufacturer:

Kalbe Farma
Concise Prescribing Info
Contents
Atorvastatin Ca
Indications/Uses
Adjunct to diet for the reduction of elevated total cholesterol, LDL-cholesterol, apolipoprotein B & triglycerides in patients w/ primary hypercholesterolemia, combined (mixed) hyperlipidemia & heterozygous & homozygous familial hypercholesterolemia when response to diet & other non pharmacological measure are inadequate.
Dosage/Direction for Use
Usual starting dose: 10 mg once/day. Dosage range: 10-80 mg once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Active liver disease or unexplained persistent serum transaminases elevation >3 x ULN. Pregnancy, women of childbearing potential not using adequate contraceptive measures & lactation.
Special Precautions
History of liver disease; heavy use of alcohol; discontinue therapy if serum transaminase levels rise to 3 x ULN & are persistent; rhabdomyolysis. Perform liver function test prior initiation, 12 wk after, during evaluation of dose & periodically thereafter. Discontinue use in case of markedly elevated CPK levels, diagnosed or suspected myopathy or w/ risk factor to development of renal failure secondary to rhabdomyolysis. Promptly report unexplained muscle pain, tenderness or weakness, especially if accompanied w/ malaise or fever. Hemorrhagic stroke. Elderly.
Adverse Reactions
Constipation, flatulence, dyspepsia, abdominal pain, headache, nausea, myalgia, asthenia, diarrhea & insomnia.
Drug Interactions
Risk of myopathy increased w/ concurrent administration of cyclosporine, fibric acid derivatives (gemfibrozil, bezafibrate, ciprofibrate, clofibrate, fenofibrate), erythromycin, azole antifungals (itraconazole, fluconazole, ketoconazole), niacin. Increased plasma conc w/ erythromycin, clarithromycin, PIs. Decreased atorvastatin plasma conc w/ antacids containing Mg & Al hydroxides & colestipol. Digoxin; OCs; fibric acid.
ATC Classification
C10AA05 - atorvastatin ; Belongs to the class of HMG CoA reductase inhibitors. Used in the treatment of hyperlipidemia.
Presentation/Packing
Form
Truvaz tab 40 mg
Packing/Price
3 × 10's (Rp440,000/boks)
Form
Truvaz tab 20 mg
Packing/Price
3 × 10's (Rp440,000/boks)
Form
Truvaz tab 10 mg
Packing/Price
3 × 10's (Rp440,000/boks)
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