Cholestyramine or aluminium hydroxide blocks the absorption of ursodeoxycholic acid.
Duration of Treatment: Pure cholesterol gallstones dissolve after a period of 6 months to 2 years. To ensure the success of therapy, bile ducts should be monitored by x-ray; if there is no change in gallstone size after 2 years, further treatment will not give good results.
Laboratory Monitor: Current scientific findings suggest that during the first 3 months of treatment for gallstone dissolution, the routine liver function tests (serum levels of transminases, bilirubin and alkaline phosphatase) should be determined fortnightly. Later, these tests need to be carried out every 3 weeks.