Vanconex

Vanconex

vancomycin

Manufacturer:

Amarox
Concise Prescribing Info
Contents
Vancomycin
Indications/Uses
Serious or severe infections caused by susceptible strains of methicillin (β-lactam)-resistant Staph. Penicillin-allergic patients, or patient who cannot receive or who have failed to respond to penicillins or cephalosporin. Infection caused by vancomycin-susceptible microorganisms. Staphylococcal, enterococci or diphtheroid endocarditis. In combination w/ rifampin, aminoglycosides or both in early-onset prosthetic valve endocarditis caused by S. epidermidis or diphtheroids.
Dosage/Direction for Use
IV Adult 500 mg 6 hrly or 1 g 12 hrly over a period of 60 min. Max: 10 mg/min. Childn 10 mg/kg 6 hrly over a period of 60 min. Infant & neonate Initially 15 mg/kg, then 10 mg/kg 12 hrly for infants in 1st wk & 8 hrly for 1 mth old infants. All doses are to be given for over a period of 60 min. Renal impairment Initial dose should be no <15 mg/kg.
Contraindications
Special Precautions
Temporary or permanent ototoxicity eg, hearing loss. Serial test of auditory function may be recommended in order to minimize risk of ototoxicity. Prolonged use may result in overgrowth of non-susceptible microorganisms. Pseudomembranous colitis can occur due to C. difficile. Monitor for leukocyte count in patients receiving IV treatment that may cause reversible neutropenia. Irritating to tissue therefore should be given IV. Co-administration of anesth agent may result to erythema & histamine-like flushing in childn. Superinfection may occur. Intrathecal eg, intralumbar or intraventricular administration. Serial monitoring of renal function in patients w/ renal dysfunction or patients receiving other aminoglycosides in order to minimize risk of nephrotoxicity. Patients w/ renal failure. Pregnancy & lactation.
Adverse Reactions
Cold, nausea, chills, urticaria, anaphylaxis, eosinophilia, neutropenia, Stevens-Johnson syndrome, vertigo, dizziness, tinnitus ototoxicity, toxic epidermal necrolysis, vasculitis, fever, hypotension, nephrotoxicity, redness of skin, thrombophlebitis, inj site pain.
Drug Interactions
Aminoglycosides inj of amphotericin B, aspirin or class of salicylates, bacitracin inj, bumetanida inj, capreomycin, carmustin, cisplatin, cyclosporin, ethacrine acid, furosemide inj, paromomycin, polymyxin, cyclizine, meclizine, phenothiazine, trimethobenzamide.
MIMS Class
ATC Classification
J01XA01 - vancomycin ; Belongs to the class of glycopeptide antibacterials. Used in the systemic treatment of infections.
Presentation/Packing
Form
Vanconex lyo powd for inj 500 mg
Packing/Price
10 × 1's
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